Clean Room Equipments

Bio Safety Cabinet

Bio Clean offers Cleanroom equipment within the Cleanroom for Biotech Pharmaceuticals, Microelectronics, Laboratory, Semi conductor units and Hospitals. We provide tailor made solution and design cleanroom equipments for specific use. The equipments are designed with durability, ease of use, compactness and aesthetics in focus. Our design engineers have incorporated many small features that differentiates our products. Our product standardization ensures the deliveries are faster, and also enables our clients, easy access to the spares of each component. Our design engineers have also worked to ensure these equipments integrate easily with our cleanroom panels.

Bio-safety cabinets are designed to provide personnel, environmental and product protection. Air flow is drawn around the operator into the front grille of the cabinet which provides personnel protection. Additionally, the downward laminar flow of HEPA-filtered air provides product protection by minimizing the chance of cross-contamination along the work surface of the cabinet. Because cabinet air passes through the exhaust HEPA filter, it is contaminant-free (environmental protection). All Class II cabinets are designed for work involving microorganisms assigned to bio safety levels 1, 2 and 3. Class II cabinets provide the microbe-free work environment necessary for cell culture propagation, and also may be used for the formulation of non-volatile antineoplastic or hemotherapeutic drugs. Bio safety cabinets are available in powder coated Galvanized Steel, SS 304 / SS 316 or a combination of both.

Two stage filtration- EU6 and EU 14
Double walled flushed Glass Side Panels
Sealed Fluorescent Lights with Milky White Diffuser
Clean Down Timer with Operation HOLD indicator
1-piece fully openable sliding toughened glass front door with counterweight arrangement

Pass Box

In pharmaceuticals manufacturing facilities, it is essential to minimise man / material movement and avoid cross contamination between different classified areas to achieve desired classification and to maintain integrity of products and processes. Pass Box is designed to allow material transfer without much personnel movement. It also aids controlling ingress of particulate contaminants into clean room and between different classified areas.

Bio Clean makes Static and Dynamic Pass Boxes meeting the customer specific requirements and to the highest standards. Option of choosing the type of pass box depends on the containment level and transfer of material from one class of cleanliness to other class of cleanliness. We also supply the pass boxes suitable for flame proof areas.

BCIAS™ Dynamic Type Pass Boxes

BCIAS™ Dynamic Type Pass Boxes designed to minimize traffic and contamination entry into the clean room, enables parts, tools and other work items to be passed to and from the room. Unit acts as an air lock device preventing ambient air from entering, or clean air from exiting the clean room. Dynamic Pass Box allows operation in sterile and particle free conditions because the continuous flushing of the working area by a unidirectional and vertical and ultra filtered airflow, it assures a full product protection.

BCIAS™ Static Type Pass Boxes

BCIAS Pass through box is designed to minimize traffic and contamination entry into the clean room, enables parts, tools and other work items to be passed to room and from the room. Unit acts as an air lock device preventing ambient air from entering, or clean air from exiting the clean room.

Air Shower Entry System

Air Shower is designed to supply Class 100 HEPA filtered air at high velocity to remove particulate matter from the person entering into the Clean Room.

Air shower is a self-contained air chamber installed at the entrance to cleanrooms in order to minimize the amount of particulate contaminants entering the cleanroom. Personnel move through the air shower while particulate contaminants are washed off with high velocity HEPA-filtered air jets. The high air velocity of 6000 FPM ensures efficient scrubbing action necessary to remove particulate matter. Contaminated air is then taken in through the base of the unit, filtered, and re-circulated into the chamber.

GENERAL SPECIFICATIONS

I Two stage filtration

o Eu6 – Prefilter (95% down to 5 micron)

o Eu14 – HEPA filter (99.999% down to 0.3micron) for return air & fresh air intake.

I Statistically and dynamically balanced motor blower with suspension arrangement to reduce noise level for suction and booster.

I S.S. 304 doors with double walled flush glass view panels & door closer

I Double skin puf filled side panels

I Horizontal internal covings at base

I Fluorescent lights with milky white diffuser

I Differential pressure gauge : 1 no

I On / off switches

I Timer for setting air shower operation time (settable for 30 seconds to 5 minutes)

I DOP test port

I 5/15 Amp switch socket for external equipment.

I Control systems – to ensure that both the doors cannot open at the same time & to ensure that both the doors will be locked during the time airflow is on.

OPERATING CONDITIONS

Air cleanliness : ISO class 5 (ISO 14644-1:1999(E))
Air velocities : 0.45 +/_ 0.05mps
Air flow : Horizontal & Vertical
Noise level : less than 67db
Vibration level : minimum
Light intensity : >300Lux
Power supply : 415V AC 3-0 50HZ

LAMINAR AIRFLOW UNIT – GARMENT STORAGE CABINET

BCIAS-GSC is designed to provide ISO class 5(class 100) particle free work station to mleet garment storage needs which avoids any particulate accumulation. The work station is continuously supplied with positive pressure HEPA filtered recirculated vertical /Horizontal air flow.

GENERAL SPECIFICATIONS

Two stage filtration

o EU6 – Prefilter (95% down to 5 micron) return & fresh air intake

o EU14 – HEPA filter (99.999% down to 0.3micron) at supply position

Statistically and dynamically balanced motor blower with suspension arrangement to reduce noise level.
U.V.Light with hour meter
IInterlocking arrangement to put off U.V.light if either door opens.
Differential pressure gauge : 1no
S.S.304 Hanging arrangements /S.S.304 removable shelves
S.S.304 doors with double walled flush glass view panels.
Heater with thermostat
On/Off switches
DOP test port
5/15 Amp switch socket for external equipment.

OPERATING CONDITIONS

Air cleanliness : ISO class 5 (ISO 14644-1:1999(E))
Air velocities : 0.45 +/_ 0.05mps
Air flow : Vertical / Horizontal / Recirculatory (Based on application)
Noise level : less than 67db
Vibration level : minimum
Power supply : 230V AC 1-0 50HZ

OPTIONS AND ACCESSORIES

Blower tripping alarms
S.S.304 Air /Gas cock
Filter blocked alarms (Audible and visible)
Velocity display with alarms (Audible and visible)
Explosion proof electrics for flame proof applications.

LAMINAR AIRFLOW UNIT – VERTICAL LAMINAR AIRFLOW UNIT

BC IAS-VLAF is designed for offering highest product protection for samples and processes by providing ISO class 5 particle free work station. VLAF offers proven protection for samples and processes. The work station is continuously supplied with positive pressure HEPA filtered vertical air flow. The vertical unidirectional airflow speed prevents contamination from operator and environment to work station. The laminarity of the flow prevents cross contamination between the items handled in the working space. BC IAS-VLAF is available in powder coated G.I steel, S.S.316, S.S.316 L or a combination of both

GENERAL SPECIFICATIONS

Glass side panels
Two stage filtration
o EU6 – Prefilters (95% down to 5 micron)
o EU14 – HEPA filter (99.999% down to 0.3micron) at supply position
Statistically and dynamically balanced motor blower with suspension arrangement to reduce noise level.
SS work table with due reinforcement
Fluorescent lights with milky white diffuser
Differential pressure gauge : 1no
On / off switches
Clean down timer with operation hold indicator
DOP test port
5/15 Amp switch socket for external equipment.

OPERATING CONDITIONS

Air cleanliness : ISO class 5 (ISO 14644-1:1999(E))
Air velocities : 0.45 +/_ 0.05mps
Air flow : Horizontal
Noise level : less than 67db
Vibration level : minimum
Light intensity : >300Lux
Power supply : 230V AC 1-0 50HZ

OPTIONS AND ACCESSORIES

A wide range of configurations to suit any containment application:

I Front doors (Hinged / Pneumatic cylinder
I U.V.Light with hour meter
IS.S.304 Air /Gas cock
I Night mode operation
I Filter blocked alarms (Audible and visible)
I Velocity display with alarms (Audible and visible)
I Explosion proof electrics for flame proof applications.

LAMINAR AIRFLOW UNIT – HORIZONTAL LAMINAR AIRFLOW UNIT

BCIAS-HLAF is designed for offering highest product protection by providing ISO class 5 particle free work station for handling critical process. HLAF offers proven protection for samples and processes.

The work station is continuously supplied with positive pressure HEPA filtered horizontal air flow. The horizontal unidirectional airflow speed prevents contamination from operator and environment to work station such as injectable medicines, cell and tissue cultures, food sample preparation for sterility testing, sterile packaging and I.V. pharmacy preparations as well as micromechanics, optics, electronics. BCIAS-HLAF is available in powder coated G.I steel, S.S.316, S.S.316 L or a combination of both.

GENERAL SPECIFICATIONS

Glass side panels
Two stage filtration
o EU6 – Prefilters (95% down to 5 micron)
o EU14 – HEPA filter (99.999% down to 0.3micron) at supply position
Statistically and dynamically balanced motor blower with suspension arrangement to reduce noise level.
SS work table with due reinforcement
Fluorescent lights with milky white diffuser
Differential pressure gauge : 1no
On / off switches
Clean down timer with operation hold indicator
DOP test port
5/15 Amp switch socket for external equipment.

OPERATING CONDITIONS &OPTIONS AND ACCESSORIES SAME AS VLAF

REVERSE LAMINAR AIR FLOW UNITS (DISPENSING / SAMPLING BOOTHS)

BCIAS-RLAF is designed for providing highest level of protection from air borne contaminants generated during powder handling operations such as sampling, charging & dispensing.

BCIAS-RLAF provides:

Operator protection
Product protection
Environment protection

The down flow booth operates on a recirculatory airflow principle providing containment by air movement. A clean, constant, laminar down flow of class 100 air is supplied in workstation suppressing any dust clouds generated during open powder processing; removing and capturing airborne from the operator's breathing zone.The prefilters at the base of the real wall capture the airborne contaminants generated. Intake velocity at prefilters increases to ensure scavenging effect.

A small percentage of air is discharged from the booth through the bleed exhaust HEPA filter to maintain the working space under negative pressure.

BCIAS-RLAF is available in powder coated G.I steel, S.S.316, S.S.316 L or a combination of both

GENERAL SPECIFICATIONS

Three stage filtration
o EU4 – Prefilters (90% down to 10 micron)
o EU7 – Intermediate filter (95% down to 3 micron)
o EU14 – HEPA filter (99.999% down to 0.3micron) at supply / exhaust
Statistically and dynamically balanced motor blower with suspension arrangement to reduce noise level.
Double skin puf filled side panels
Horizontal internal covings at base
Fluorescent lights with milky white diffuser
Differential pressure gauge : 3 nos
On / off switches
Clean down timer with operation hold indicator
DOP test port
5/15 Amp switch socket for external equipment.

OPERATING CONDITIONS

Air cleanliness : ISO class 5 (ISO 14644-1:1999(E))
Air velocities : 0.45 +/_ 0.05mps
Air flow : Vertical – Recirculatory
Noise level : less than 67db
Vibration level : minimum
Light intensity : >300Lux
Power supply : 230V AC 1-0 50HZ / 415V AC 3-0 50HZ

OPTIONS AND ACCESSORIES

Stainless steel perforated grille for supply HEPA filters
Front antistatic PVC curtains (for ware house applications)
Front doors (Hinged / Sliding/Rapid roller)
S.S stand alone table for keeping weighing scale
Sodium vapor lamps I night mode operation
Filter blocked alarms (Audible and visible)
Velocity display with alarms (Audible and visible)
Explosion proof electrics for flame proof applications.
PLC based control system
Once through airflow systems
Safe change Bag in / Bag out arrangement for filters.
Double skin side panels with view windows

FILTERS - PRE FILTERS

3 micron prefilter.
5 micron prefilter.
10 micron prefilter.

High particle Air/Gas passes through PREFILTER to remove particles down to 5 micron from air/gas flow with efficiency exceeding 60-65% And 3 micron from air/gas flow with efficiency exceeding 70-75%. Prefilter is ASHRAE STD 52-76 equivalent to 98% on BS 2831 Test Dust II. The prefilter exclusive design ensures a large filtrating area in ratio to the face area. The filter element is constructed from ”GLASS FIBER” paper. It is unique properties are…

PROPERTIES OF PREFILTERS

Resists to mildew.
Resists to fungal.
Resists to corrosive chemical fumes.
Resists to bacteria.
Resists to hydrofluoric acid.

The fiber glass is sandwiched between 2 layers for 5 micron and 1 layer for 10 micron. The filter media is fire retardant type. The filter house is made from stainless steel sheet frame with flange and bonded on side using long life adhesive.

FEATURES OF PREFILTERS & HEPA FILTER

Easy Handling
Easy Install
Easy Removable
Easy Cleaning
Use to Temp Range (100° to 600°C)

HEPA FILTERS

Minipleat HEPA filters
High temperature HEPA filter
Aluminum HEPA filters.(100% DOP)
Aluminum HEPA filters.(50% DOP)

High particle Air/Gas passes through HEPA FILTER to remove particles down to 0.3 micron from air/gas flow with efficiency exceeding 99.97%. The HEPA filter exclusive design ensures a large filtrating area in ratio to the face area. The filter element is constructed from “non woven fiber glass media” paper. It is unique properties are… HEPA filter has high particles or dust retention capacity and high flow rate.

HEPA filter units are made in standard size and are interchangeable. The filter media is fire retardant type. The filter media is assembled in a rigid frame made of aluminum section with locking insert and bonded to the frame on all sides using fire retardant type adhesive. A fire retardant gasket is used to avoid leakages. Each HEPA filter is to test conforming to international standards IES-RP-CC-001-86.

TECHNICAL SPECIFICATION

Clean Level 1 00 particles of size 0.5 microns/ F3
ISO Class 5(ISO 14644-1: 1999(E))
Air Velocity 90 FPM (0.45MPS)+- 20%
Noise Level <65 DB (A scale)
Vibration <2.5m (0.0001 ")

ULPA FILTERS

ULPA stands for ultra-low particulate air. Growing market demand from advanced science and technology led to development of ULPA filters which provide a minimum of 99.999% efficiency (0.001% maximum penetration) on 0.3micron particles for achieving better cleanliness classes and cleaner working environments. These are used for ultra-clean rooms, where contamination levels have to be controlled at levels better than that which can be achieved with conventional HEPA filters. Boron free ULPA filters of 99.9997% efficiency for particles down to 0.12 micron size for class 10 and class 1 clean rooms are specially used in electronic / semiconductors / wafer manufacturing industries, where tolerance to contamination level above 0.12micron is also very critical and not permitted.

Note that the text information for instance on the efficiency @ 99.97% and 99.997% of HEPA filters look similar but in reality the difference is not insignificant. A 99.97% efficient filter has a fractional penetration of 0.0003; while a 99.99% filters fractional penetration is 0.0001. This means that a 99.99% filter is 3 times more efficient in removing 0.3micron particles.

CLEAN ROOM CLOTHING

People who work in cleanrooms undergo extensive training to maintain the cleaning standards.

They enter and exit the cleanroom through by wearing special clothes designed to trap contaminants which are shed by the bodies of people working in the clean rooms.

Depending on the complexity & classification of clean room, clean room clothing could be as extensive as fully covered in multiple layered dresses with self contained breathing apparatus.

Cleanroom clothing is used to prevent microbes, particles from being released off the wearer’s body and contaminating the environment. The cleanroom clothing must not release any kind of particles or fibers to prevent contamination of the environment.

So much so is the importance of clean room clothing, that in case if the same is not being maintain, it can certainly degrade the performance of semi conductors and can lead to cross infection between pateints and healthy people in Pharmaceuticals or Medical Industries.